NUMERICAL SIMULATION OF THE 2017 XINMO CATASTROPHIC LANDSLIDE CONSIDERING ENTRAINMENT EFFECT


Cross-sectional and longitudinal genotype to phenotype surveillance of SARS-CoV-2 variants over the first four years of the COVID-19 pandemicResearch in context

Summary: Background: Continued phenotyping and ongoing molecular epidemiology are important in current and future monitoring of emerging SARS-CoV-2 lineages.Herein we developed pragmatic strategies to track the emergence, spread and phenotype of SARS-CoV-2 variants in Australia in an era of decreasing diagnostic PCR testing and focused cohort-based

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Natural variation in the consequences of gene overexpression and its implications for evolutionary trajectories

Copy number variation through gene or chromosome amplification provides a route for rapid phenotypic variation and supports the long-term evolution of gene functions.Although the evolutionary importance of copy-number variation is known, little is understood about how genetic background influences its tolerance.Here, we measured fitness costs of ov

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